3 forms of ZOMIG

Which form of ZOMIG is best for you?

Use this information to help discuss with your health care professional what form of ZOMIG is best for you.

Learn more about each form:

Or use the Formulation Finder—an easy-to-use chart with facts about the 3 forms of ZOMIG.

Click on each tab for information about each form.

  • ZOMIG® Tablets
    Type of headache Moderate or severe migraine Moderate or severe migraine
    Dosage ZOMIG Tablets 2.5 mg or placebo ZOMIG Tablets 5 mg or placebo
    Time that moderate or severe headache was said to change to mild or painless 45 minutes
    For 24.5% taking ZOMIG Tablets 2.5 mg
    For 12.4% taking placebo
    2 hours
    For 58.9% taking ZOMIG Tablets 2.5 mg
    For 34.6% taking placebo     		45 minutes
    For 26.9% taking ZOMIG Tablets 5 mg
    For 17.3% taking placebo
    2 hours
    For 62.1% taking ZOMIG Tablets 5 mg
    For 36% taking placebo
    Number of patients in study 487 taking ZOMIG Tablets 2.5 mg
    247 taking placebo     		482 taking ZOMIG Tablets 5 mg
    252 taking placebo

    ZOMIG Tablets: convenience in a conventional tablet

    • Provides fast, powerful migraine relief in tablet form
    • Available in 2.5-mg and 5-mg doses

    Headache response* as early as 45 minutes with ZOMIG Tablets 2.5 mg and 5 mg

    In the only direct comparison of ZOMIG 2.5 mg and 5 mg, there was little added benefit from the larger dose, but side effects were generally increased at 5 mg.

    * Headache response is defined as a moderate or severe headache improving to mild or no pain.

  • ZOMIG-ZMT®
    Type of headache Moderate or severe migraine Moderate or severe migraine
    Dosage ZOMIG-ZMT 2.5 mg or placebo ZOMIG-ZMT 5 mg or placebo
    Time that moderate or severe headache was said to change to mild or painless 1 hour
    For 45% taking ZOMIG-ZMT 2.5 mg
    For 19% taking placebo
    2 hours
    For 63% taking ZOMIG-ZMT 2.5 mg
    For 22% taking placebo     		30 minutes
    For 16.5% taking ZOMIG-ZMT 5 mg
    For 12.5% taking placebo
    2 hours
    For 59% taking ZOMIG-ZMT 5 mg
    For 30.6% taking placebo
    Number of patients in study 231 taking ZOMIG-ZMT 2.5 mg
    239 taking placebo     		329 taking ZOMIG-ZMT 5 mg
    341 taking placebo

    ZOMIG-ZMT Orally Disintegrating Tablets: you don't need water to take it

    • Fast, powerful relief in a form that quickly dissolves on your tongue
    • Good for situations when you can’t take your migraine medication because you don’t have water—at work or dropping the kids at school
    • A suitable option if you experience nausea caused by the migraine attack
    • Available in 2.5-mg and 5-mg doses

    Headache response* as early as 30 minutes with ZOMIG-ZMT 5 mg

    * Headache response is defined as a moderate or severe headache improving to mild or no pain.

  • ZOMIG® Nasal Spray
    Type of headache Moderate or severe migraine
    Dosage ZOMIG Nasal Spray 5 mg or placebo
     






     
    • A great option for your busy life when you want to keep your medication handy
    • Available in a 5-mg dose

    How to use ZOMIG Nasal Spray


Formulation Finder

Find the form of ZOMIG that's best for you

ZOMIG nasal spray

Print Formulation Finder PDF Opens in new window (PDF — 295KB)

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Find more information about each form of ZOMIG: ZOMIG Tablets, ZOMIG-ZMT Orally Disintegrating Tablets, or ZOMIG Nasal Spray.

Important Safety Information

ZOMIG is a prescription medication used for the treatment of migraine headaches in adults. ZOMIG is not for the prevention of migraines.

  • Do not take ZOMIG if your headache is not a migraine
  • Do not take ZOMIG if your headache is hemiplegic or basilar migraine (If you are unsure about this, ask your doctor)
  • Do not take ZOMIG if you have heart disease, history of, or risk factors for heart disease, uncontrolled high blood pressure, circulation (blood flow) problems, or have had a stroke. Only your doctor can determine if ZOMIG is right for you
  • ZOMIG should not be used within 24 hours of another 5-HT1 agonist (triptans), ergotamine-containing or ergot-type medication (for headache), or within 2 weeks of an MAO-A inhibitor (for depression)
  • Talk to your doctor if you are pregnant, planning to become pregnant, or breastfeeding because ZOMIG may not be right for you
  • ZOMIG, like other triptans, may be associated with a potentially life-threatening condition called serotonin syndrome, mainly when taken together with certain antidepressants. Inform your doctor of all your medications prior to taking ZOMIG
  • Phenylketonurics: ZOMIG-ZMT® (zolmitriptan) Orally Disintegrating Tablets contain phenylalanine, a component of aspartame
  • Safety and effectiveness of ZOMIG in pediatric patients have not been established
  • Side Effects: The most common side effects reported by patients in clinical trials with ZOMIG Nasal Spray include unusual taste, tingling sensation, skin sensitivity, and dizziness
  • Side Effects: The most common side effects reported by patients in clinical trials with ZOMIG Tablets and ZOMIG-ZMT include dizziness; tightness, pressure, pain in the neck, throat, or jaw; fatigue; tingling; drowsiness; and nausea

Talk to your doctor about prescription ZOMIG.

Read the full Prescribing Information for ZOMIG Nasal Spray Opens in new window (PDF — 122KB)

Read the full Prescribing Information for ZOMIG Tablets and ZOMIG-ZMT Opens in new window (PDF — 194KB)

Read the Consumer-Friendly Brief Summary Opens in new window (PDF — 480KB)

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.FDA.gov/medwatch or call 1-800-FDA-1088.